Dr. Burton Dickey, a pulmonary expert, noted that patients with bronchiectasis face escalating health risks when infections arise. This can lead to pneumonia and, notably, enhance the likelihood of blood clot formation, further increasing stroke risk. The pope's recent hospitalization for pneumonia may have compounded these issues.

The Vatican's announcement cited the stroke as the immediate cause of death, which precipitated a “cardiocirculatory collapse.” According to Dr. Michelle Kittleson, a cardiology professor, this can occur when a stroke impairs the brain areas responsible for regulating heart function or causes swelling that disrupts normal bodily operations.

As news of his passing spreads, mourners are gathering at St. Peter's Square and tributes pour in from around the world, reflecting on Pope Francis's impact and legacy during his reign. Memorial services and tributes are set to honor the life and contributions of the late pontiff.