Annette Dionne, the last surviving sister of the Canadian quintuplets, has died at 91, the Dionne Quints Home Museum has announced.

The five identical sisters, born in Ontario at the height of the Great Depression in 1934, were the first known quintuplets to survive past infancy.

They quickly became a global sensation during their childhood - starring in feature films, appearing on magazine covers, and endorsing products from toothpaste to syrup.

Much beloved, Annette had championed children's rights, the museum said in a statement announcing her death.

Annette,

The museum seeks to preserve their legacy and educate the public on the quintuplets' controversial upbringing, adding: She believed it was important to maintain the Dionne Quints Museum and the history it provides for the future of all children.

The quintuplets - Annette, Yvonne, Cécile, Émilie, and Marie - were taken away from their parents by the Ontario government when they were infants. For several years, the authorities displayed the children in a compound dubbed Quintland, which became a popular tourist attraction. The children were closely observed and had limited contact with their parents.

Later, the children regained custody of the quintuplets.

As adults, Annette, Cécile, and Yvonne sued the Ontario government for compensation over their upbringing, receiving nearly C$3 million in 1998. Annette was the last surviving sibling out of the 14 Dionne children.

She is survived by her legacy and the memory of her family's unique journey, as she joins her late sisters Émilie, Marie, and Yvonne, who passed away in earlier years.